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Archivi categoria: Linee Guida

Metabolic Acidosis in CKD: Core Curriculum 2019 – American Journal of Kidney Diseases

Maintenance of normal acid-base homeostasis is one of the most important kidney functions. In chronic kidney disease, the capacity of the kidneys to excrete the daily acid load as ammonium and titratable acid is impaired, resulting in acid retention and metabolic acidosis. The prevalence of metabolic acidosis increases with declining glomerular filtration rate. Metabolic acidosis is associated with several clinically important complications, including chronic kidney disease progression, bone demineralization, skeletal muscle catabolism, and mortality.

Sorgente: Metabolic Acidosis in CKD: Core Curriculum 2019 – American Journal of Kidney Diseases

 
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Pubblicato da su 21 gennaio 2020 in letteratura, Linee Guida

 

Carcinoma della prostata | Univadis

Linea guida – Edizione 2019 – Aggiornata a ottobre 2019

Sorgente: Carcinoma della prostata | Univadis

 
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Pubblicato da su 3 gennaio 2020 in letteratura, Linee Guida

 

Hypertension in adults: summary of updated NICE guidance | The BMJ

### What you need to know Hypertension is a leading global cause of morbidity and mortality. More than 25% of the adult UK population has hypertension, and in about 30% blood pressure remains uncontrolled.1 In August, the National Institute for Health and Care Excellence (NICE) published its updated guideline on the diagnosis and management of hypertension. The guideline reviews further evidence that has emerged since it was last updated in 2011 from randomised trials investigating the initiation, monitoring, and choice of antihypertensive treatment. The scope of the updated guideline has increased to also include people with type 2 diabetes, but does not make recommendations for people with chronic kidney disease, established cardiovascular disease, or hypertension in pregnancy. This article summarises the most recent recommendations from NICE and includes information considered to be most relevant to primary care clinicians. Key changes to current practice include offering drug treatment to people at a lower threshold for 10 year risk of cardiovascular disease, emphasis on maintaining blood pressure below target, and clarifying criteria for same day specialist review in people

Sorgente: Hypertension in adults: summary of updated NICE guidance | The BMJ

 
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Pubblicato da su 23 ottobre 2019 in letteratura, Linee Guida

 

Conflitti d’interesse in medicina – SaluteInternazionale

Gianna MilanoNegli anni la soglia di sicurezza nel sangue per il colesterolo è stata via via abbassata da linee guida (tutt’altro che limpide), ampliando a dismisura il bacino dei candidati al consumo delle statine.

Sorgente: Conflitti d’interesse in medicina – SaluteInternazionale

 

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Dysproteinemia and the Kidney: Core Curriculum 2019 – ScienceDirect

Dysproteinemic kidney diseases occur when B- or plasma cell clones produce pathogenic monoclonal immunoglobulins or light chains that cause kidney dam…

Sorgente: Dysproteinemia and the Kidney: Core Curriculum 2019 – ScienceDirect

 
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Pubblicato da su 15 agosto 2019 in letteratura, Linee Guida

 

The Use of Erythropoiesis-Stimulating Agents in Patients With CKD and Cancer: A Clinical Approach – American Journal of Kidney Diseases

Erythropoiesis-stimulating agents (ESAs) have been used to manage anemia in chronic kidney disease (CKD) to reduce transfusion requirements and anemia symptoms. Lack of objective benefit of normalizing hemoglobin (Hb) levels and increased evidence of ESA-induced complications in persons with anemia has resulted in clinicians generally attempting to maintain Hb levels in the 10- to 11-g/dL range. In 2000, concerns in patients with cancer arose attributable to associations of ESA use with increased mortality, thrombotic complications, and cerebrovascular accidents led to a change in US Food and Drug Administration oncology guidelines regarding limitation of ESA use for chemotherapy-induced anemia.

Sorgente: The Use of Erythropoiesis-Stimulating Agents in Patients With CKD and Cancer: A Clinical Approach – American Journal of Kidney Diseases

 

Handbook_Competenze_core_per_l_Evidence-based_Practice.pdf

Sorgente: Handbook_Competenze_core_per_l_Evidence-based_Practice.pdf

 
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Pubblicato da su 1 agosto 2019 in letteratura, Linee Guida

 
 
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