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The Controversy of Contrast-Induced Nephropathy With Intravenous Contrast: What Is the Risk? – American Journal of Kidney Diseases

Contrast-induced nephropathy (CIN) has long been observed in both experimental and clinical studies. However, recent observational studies have questioned the prevalence and severity of CIN following intravenous contrast exposure. Initial studies of acute kidney injury following intravenous contrast were limited by the absence of control groups or contained control groups that did not adjust for additional acute kidney injury risk factors, including prevalent chronic kidney disease, as well as accepted prophylactic strategies.

Sorgente: The Controversy of Contrast-Induced Nephropathy With Intravenous Contrast: What Is the Risk? – American Journal of Kidney Diseases

 
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Pubblicato da su 18 ottobre 2019 in AKI, malattie renali

 

Timing of Recovery From Moderate to Severe AKI and the Risk for Future Loss of Kidney Function – American Journal of Kidney Diseases

The extent of recovery of kidney function following acute kidney injury (AKI) is known to be associated with future chronic kidney disease. Less is known about how the timing of recovery affects the rate of future loss of kidney function.

Sorgente: Timing of Recovery From Moderate to Severe AKI and the Risk for Future Loss of Kidney Function – American Journal of Kidney Diseases

 
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Pubblicato da su 18 ottobre 2019 in AKI, malattie renali

 

Association of Acute Increases in Plasma Creatinine after Renin-Angiotensin Blockade with Subsequent Outcomes | American Society of Nephrology

Background and objectives Data from observational and interventional studies provide discordant results regarding the relationship between creatinine increase after renin-angiotensin system inhibition (RASi) and adverse outcomes. We compared health outcomes among patients with different categories of increase in creatinine upon initiation of RASi in a large population-based cohort. Design, setting, participants, & measurements We performed a retrospective analysis of the Stockholm CREAtinine Measurements database, which contains complete information on diagnoses, medication dispensation claims, and laboratory test results for all Stockholm citizens accessing health care. Included were 31,951 adults initiating RASi during 2007–2011 with available pre- and postinitiation creatinine monitoring. Multivariable Cox regression was used to compare mortality, cardiovascular and ESKD events among individuals with different ranges of creatinine increases within 2 months after starting treatment. Results In a median follow-up of 3.5 years, acute increases in creatinine were associated with mortality (3202 events) in a graded manner: compared with creatinine increases <10%, a 10%–19% increase

Sorgente: Association of Acute Increases in Plasma Creatinine after Renin-Angiotensin Blockade with Subsequent Outcomes | American Society of Nephrology

 

Kidney Damage in Younger Adults Tied to NSAID Use – Renal and Urology News

Individuals taking a certain number of NSAIDs each month had greater risks of acute kidney injury and chronic kidney disease.

Sorgente: Kidney Damage in Younger Adults Tied to NSAID Use – Renal and Urology News

 

Trattate bene i vostri reni. Anche un piccolo danno può diventare irreversibile | HealthDesk

Uno studio firmato da un team dell’Università di Firenze e dell’ospedale pediatrico Meyer rivoluziona le conoscenze sul danno renale acuto (fino a qualche anno fa definito insufficienza renale acuta),

Sorgente: Trattate bene i vostri reni. Anche un piccolo danno può diventare irreversibile | HealthDesk

 

Contrast-Induced Nephropathy: Is the Concern Exaggerated? | Kidney News

Intravascular iodinated contrast has historically been considered a risk factor for acute kidney injury (AKI), particularly among individuals with underlying chronic kidney disease (1). Recent studies, however, have suggested that incidence of contrast-induced nephropathy (CIN) may not be as frequent as previously thought (2,3). In this commentary, we argue that contrast material can often be safely used without increased risk of AKI, even among individuals with underlying kidney disease.

Sorgente: Contrast-Induced Nephropathy: Is the Concern Exaggerated? | Kidney News

 
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Pubblicato da su 23 aprile 2018 in AKI, malattie renali

 

Management of Acute Kidney Injury: Core Curriculum 2018 – American Journal of Kidney Diseases

Sorgente: Management of Acute Kidney Injury: Core Curriculum 2018 – American Journal of Kidney Diseases

 
 
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